PT-141 10mg
Bremelanotide (PT-141) — 10mg
Used to treat sexual dysfunction, PT-141 enhances libido, arousal, and sexual performance in both men and women. It acts via melanocortin receptors in the brain, unlike PDE5 inhibitors.
Lyophilized sterile powder in a glass vial.
For dilution with bacteriostatic water or sterile water for injection.
Store refrigerated. Once reconstituted, it remains stable for 30 days if kept cold and sterile.
What is PT-141 (Bremelanotide)?
PT-141 is a synthetic peptide derived from Melanotan II. Unlike PDE5 inhibitors (like Viagra), PT-141 acts on the central nervous system, specifically melanocortin receptors (MC3 and MC4), to stimulate arousal, libido, and sexual response in both sexes.
It is FDA-approved under the name Vyleesi for female hypoactive sexual desire disorder (HSDD), and is widely used off-label by men and women seeking libido enhancement.
Benefits of PT-141 10mg
The benefits of PT-141 go beyond traditional sexual enhancement. Notable effects include:
● Increases libido and sexual desire
● Improves erectile function (men)
● Enhances sexual satisfaction (men and women)
● Works via CNS, not blood flow (unlike PDE5 drugs)
● May benefit antidepressant-induced sexual dysfunction
● Rapid onset of action (15 min – 2 hrs)
Possible Side Effects of PT-141
Though generally well-tolerated, PT-141 may cause:
Nausea
Facial flushing
Headache
Increased blood pressure (mild)
Injection site irritation
Rare/less common effects:
- Vomiting (dose-related)
- Fatigue
- Darkening of skin with prolonged use (from melanocortin activity)
PT-141 Dosage Guidelines
Dosing can vary by user experience and desired intensity. Start low and titrate upward to find optimal response.
● Standard dosage:
- 1 mg to 2 mg subcutaneously
- Inject ~45 minutes to 2 hours before sexual activity
● Max usage:
- No more than 3× per week recommended
● Microdosing (for daily libido):
- 250–500 mcg daily or every other day (off-label)
Route: Subcutaneous injection, typically in the lower abdomen or thigh.
Best Practices with PT-141
- Use small-gauge insulin syringes (31G recommended)
- Inject on an empty stomach to reduce nausea
- Stay hydrated
- Store reconstituted vial refrigerated
- Wait 24–48 hours between doses to assess effects
Lifestyle and Dietary Considerations
While not required, supporting overall hormonal health can optimize PT-141 effects:
- Balanced diet rich in omega-3s, zinc, and B-vitamins
- Reduce alcohol intake (especially around dosing)
- Exercise regularly to support circulation and CNS function
- Prioritize sleep — neuropeptide response is sleep-dependent
- Manage stress, as cortisol blunts sexual function
When combined with healthy lifestyle choices, PT-141 can be a safe and powerful aid in restoring or enhancing sexual wellness.
